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In this compelling audiobook, Oprah Winfrey shares her lifelong struggles with weight and explores the groundbreaking insights from Dr. Ania Jastreboff of Yale School of Medicine. Together, they reveal obesity as a disease influenced by biology rather than willpower, and discuss new medications that can help reset our body's fat set point. Dr. Jastreboff offers practical strategies for optimizing health and highlights the transformative effects of treatment, including a reduction in intrusive thoughts about food. This work combines science and empathy, presenting a hopeful path toward healing and improved overall well-being.